|
KMID : 0370220100540020134
|
|
Yakhak Hoeji
2010 Volume.54 No. 2 p.134 ~ p.141
|
|
|
The Inflammation-modulatory Effects of Ginseng Saponin and Polysaccharide on Activated RAW264.7 Cell-line
|
|
Lee Do-Ik
|
|
|
Abstract
|
|
|
|
It is well known that the numbers and functions of immune-associated cells are increased by saponins and polysaccharides in ginseng. In this study, the mixture of polysaccharide and saponin (MPS) from Panax ginseng is applied to LPS- activated RAW 264.7 cells. The production of NO and the gene expression of IL-6 and TNF- are decreased in LPSactivated RAW 264.7 cells and the expression of arginase II and PD-1L genes is decreased in LPS-untreated macrophages. Therefore, the mixture of saponin and polysaccharide from Panax ginseng could be used in order to regulate immune responses.
|
|
|
KEYWORD
|
|
|
saponin, Polysaccharide, mixture, inflammation, immunosuppression
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|